Manjunatha, Ujjini: search on Z-Library

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1

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Manjunatha, Ujjini H., Vinayak, Sumiti, Zambriski, Jennifer A., Chao, Alexander T., Sy, Tracy, Noble, Christian G., Bonamy, Ghislain M. C., Kondreddi, Ravinder R., Zou, Bin, Gedeck, Peter, Brooks, Car

Journal:

Year:

2017

Language:

english

File:

PDF, 5.48 MB

english, 2017

2

Perspective: Challenges and opportunities in TB drug discovery from phenotypic screening

Manjunatha, Ujjini H., Smith, Paul W.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.42 MB

english, 2014

3

Structure−Activity Relationships of Antitubercular Nitroimidazoles. 1. Structural Features Associated with Aerobic and Anaerobic Activities of 4- and 5-Nitroimidazoles

Kim, Pilho, Zhang, Liang, Manjunatha, Ujjini H., Singh, Ramandeep, Patel, Sejal, Jiricek, Jan, Keller, Thomas H., Boshoff, Helena I., Barry, Clifton E., Dowd, Cynthia S.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 275 KB

english, 2009

4

The mechanism of action of PA-824

Manjunatha, Ujjini, Boshoff, Helena I.M., Barry, Clifton E.

Journal:

Communicative & Integrative Biology

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

5

A complex of DNA gyrase and RNA polymerase fosters transcription in Mycobacterium smegmatis

Richa Gupta, Arnab China, Ujjini H. Manjunatha, N.M. Ponnanna, Valakunja Nagaraja

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 354 KB

english, 2006

6

The impact of genomics on discovering drugs against infectious diseases

Helena I.M. Boshoff, Ujjini H. Manjunatha

Journal:

Microbes and Infection

Year:

2006

Language:

english

File:

PDF, 245 KB

english, 2006

7

A novel F 420 -dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

Gurumurthy, Meera, Rao, Martin, Mukherjee, Tathagata, Rao, Srinivasa P. S., Boshoff, Helena I., Dick, Thomas, Barry, Clifton E., Manjunatha, Ujjini H.

Journal:

Molecular Microbiology

Year:

2013

Language:

english

File:

PDF, 924 KB

english, 2013

8

Fishing the Target of Antitubercular Compounds: In Silico Target Deconvolution Model Development and Validation

Prathipati, Philip, Ma, Ngai Ling, Manjunatha, Ujjini H., Bender, Andreas

Journal:

Journal of Proteome Research

Year:

2009

Language:

english

File:

PDF, 5.75 MB

english, 2009

9

Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents

Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat,

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 562 KB

english, 2013

10

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

Thomas Dick, Ujjini Manjunatha, Barbara Kappes, Martin Gengenbacher

Journal:

Molecular Microbiology

Year:

2010

Language:

english

File:

PDF, 609 KB

english, 2010

11

Evaluating the Sensitivity of Mycobacterium tuberculosis to Biotin Deprivation Using Regulated Gene Expression

Woong Park, Sae, Klotzsche, Marcus, Wilson, Daniel J., Boshoff, Helena I., Eoh, Hyungjin, Manjunatha, Ujjini, Blumenthal, Antje, Rhee, Kyu, Barry, Clifton E., Aldrich, Courtney C., Ehrt, Sabine, Schna

Journal:

Year:

2011

Language:

english

File:

PDF, 640 KB

english, 2011

12

Corrections to Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships

Kim, Pilho, Kang, Sunhee, Boshoff, Helena I., Jiricek, Jan, Collins, Margaret, Singh, Ramandeep, Manjunatha, Ujjini H., Niyomrattanakit, Pornwaratt, Patel, Sejal, Zhang, Liang, Goodwin, Michael, Dick,

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 558 KB

english, 2009

13

Structure–Activity Relationships of Antitubercular Nitroimidazoles. 3. Exploration of the Linker and Lipophilic Tail of ((S)-2-Nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-Amino PA-824).

Cherian, Joseph, Choi, Inhee, Nayyar, Amit, Manjunatha, Ujjini H., Mukherjee, Tathagata, Lee, Yong Sok, Boshoff, Helena I., Singh, Ramandeep, Ha, Young Hwan, Goodwin, Michael

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

14

[RSC Drug Discovery] Drug Discovery from Natural Products || Chapter 14. Natural Products: New Agents Against MDR Tuberculosis

Manjunatha*, Ujjini

Year:

2012

Language:

english

File:

PDF, 292 KB

english, 2012

15

Drug discovery for the developing world: progress at the Novartis Institute for Tropical Diseases

Jones, Catherine L., Yeung, Bryan K. S., Manjunatha, Ujjini, Shi, Pei-Yong, Bodenreider, Christophe, Diagana, Thierry T.

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 157 KB

english, 2015

16

Corrrection to Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Novel Antitubercular Agents

Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat,

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 121 KB

english, 2014

17

Development of a novel cytopathic effect-based phenotypic screening assay against Cryptosporidium

Chao, Alexander T., Lee, Boon Heng, Wan, Kah Fei, Selva, Jeremy, Zou, Bin, Gedeck, Peter, Beer, David, Diagana, Thierry T., Bonamy, Ghislain, Manjunatha, Ujjini H.

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

18

Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships

Kim, Pilho, Kang, Sunhee, Boshoff, Helena I., Jiricek, Jan, Collins, Margaret, Singh, Ramandeep, Manjunatha, Ujjini H., Niyomrattanakit, Pornwaratt, Zhang, Liang, Goodwin, Michael, Dick, Thomas, Kelle

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

19

A continuous fluorescence displacement assay for BioA: An enzyme involved in biotin biosynthesis

Daniel J. Wilson, Ce Shi, Benjamin P. Duckworth, Joseph M. Muretta, Ujjini Manjunatha, Yuk Y. Sham, David D. Thomas, Courtney C. Aldrich

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

20

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase From a Fragment Hit Using Structure-Based Drug Design

Yokokawa, Fumiaki, Nilar, Shahul, Noble, Christian G., Lim, Siew Pheng, Rao, Ranga, Tania, Stefani, Wang, Gang, Lee, Gladys, Hunziker, Juerg, Karuna, Ratna, Manjunatha, Ujjini H., Shi, Pei-Yong, Smith

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.77 MB

english, 2016

21

Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Xiaojin Li, Ujjini H. Manjunatha, Michael B. Goodwin, John E. Knox, Christopher A. Lipinski, Thomas H. Keller, Clifton E. Barry III, Cynthia S. Dowd

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 486 KB

english, 2008

22

Structure−Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5 R )-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium t uberculosis and Escherichia c oli

Kim, Pilho, Zhang, Yong-Mei, Shenoy, Gautham, Nguyen, Quynh-Anh, Boshoff, Helena I., Manjunatha, Ujjini H., Goodwin, Michael B., Lonsdale, John, Price, Allen C., Miller, Darcie J., Duncan, Ken, White,

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 396 KB

english, 2006

23

Cryptosporidiosis Drug Discovery: Opportunities and Challenges

Manjunatha, Ujjini H., Chao, Alexander T., Leong, F. Joel, Diagana, Thierry T.

Journal:

ACS Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 1.00 MB

english, 2016

24

Innovations in addressing pediatric diarrhea in low resource settings

Jumani, Rajiv S, Spector, Jonathan M, Izadnegahdar, Rasa, Kelly, Paul, Diagana, Thierry T., Manjunatha, Ujjini H.

Journal:

ACS Infectious Diseases

Year:

2019

Language:

english

File:

PDF, 2.19 MB

english, 2019

25

Structure Activity Relationships of 4-Hydroxy-2-pyridones: a Novel Class of Antituberculosis Agents

Ng, Pearly Shuyi, Manjunatha, Ujjini H., Rao, Srinivasa PS., Camacho, Luis R., Ma, Ngai Ling, Herve, Maxime, Noble, Christian G., Goh, Anne, Peukert, Stefan, Diagana, Thierry T., Smith, Paul W., Kondr

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

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